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Date
10/12/2011 14:13:29
Group number
PI name
Messeguer, A.
Channel family
nuclear receptor subfamily 3, group C, member 2" (código del gen NR3C2).
Channel name
nuclear receptor subfamily 3, group C, member 2" (código del gen NR3C2).
Channel subunit
UNIPROT
Relevant publication (1)
Relevant publication (2)
Relevant publication (3)
CD
FTIR
NMR
Absorbance /
Fluorescence
Interaction protein (1)
Interaction protein (2)
Interaction protein (3)
Interaction protein (4)
PDB (1)
PDB (2)
PDB (3)
Expression tissues
Expression cell lines
Expression plasmids
Level of expression
Channel quaternary
Agonists
Screening by group P11 of a library of N-alkylglycine pentamers (peptoids) constructed under the positional scanning format, followed by deconvolution led to the identification of compounds that induce a positive allosteric response on the effect of aldosterone on the mineralcorticoid receptor. Two compounds have been identified as the most active, although these results must be confirmed.
Smile agonist
Antagonists and blockers
Smile antagonist
Structure-function
relationship
Molecular determinant assembly
Molecular determinant clustering
Molecular determinant trafficking
Molecular determinant binding
Mutants constructs
Antibodies
Diseases

 

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